Ask Jacki About Health, Stem Cells & Changing Lives


Stem Cell Scientists Make Case For More Research To Defeat Diseases

Over the last few years more scientists are learning what Christian Drapeau and STEMTech have known for years….that adult stem cells make up our bodies renewal system and we can naturally increase their numbers by taking Stem Enhance. Increase your circulating stem cells for optimal health.

Leading stem cell scientists make an impassioned case for renewing humanity and defeating disease.

Stem cell breakthrough may offer possible cures for Diabetes, Parkinson’s disease

Posted in Adult Stem Cell Research,Adult Stem Cells by Jacki Smith on March 14, 2009
Tags: , , , , , , ,

London, March 2 (ANI): Scientists have reached a step closer to developing potential treatments for devastating diseases including spinal cord injury, macular degeneration, diabetes and Parkinson’s disease, thanks to a new method of creating stem cells discovered by researchers at Mount Sinai Hospital in Canada.

The researchers say that their study accelerates stem cell technology, and provides a road map for new clinical approaches to regenerative medicine.

“We hope that these stem cells will form the basis for treatment for many diseases and conditions that are currently considered incurable,” Nature magazine quoted Dr. Andras Nagy, Senior Investigator at the Samuel Lunenfeld Research Institute of Mount Sinai Hospital, Investigator at the McEwen Centre for Regenerative Medicine, and Canada Research Chair in Stem Cells and Regeneration, as saying.

“This new method of generating stem cells does not require embryos as starting points and could be used to generate cells from many adult tissues such as a patient’s own skin cells,” the researcher added.

Dr. Nagy revealed that his method helps create pluripotent stem cells-which can develop into most other cell types-without disrupting healthy genes. The researcher added that the method involves a novel wrapping procedure to deliver specific genes to reprogram cells into stem cells.

Scientists have to date relied upon approaches that requite the use of viruses to deliver the required genes, a method that carries the risk of damaging the DNA.

Given that Dr. Nagy’s method does not require viruses, it overcomes a major hurdle for the future of safe, personalized stem cell therapies in humans.

“This research is a huge step forward on the path to new stem cell-based therapies and indicates that researchers at the Lunenfeld are at the leading edge of regenerative medicine,” said Dr. Jim Woodgett, Director of Research for the Samuel Lunenfeld Research Institute of Mount Sinai Hospital.

Regenerative medicine refers to enabling the human body to repair, replace, restore and regenerate its own damaged or diseased cells, tissues and organs. (ANI)

Will Obama’s Stem Cell Announcement Doom Promising Adult Stem Cell Research? — Stem Cell Business Community Suggests Adult Stem Cell Advances Could Be Lost as Embryonic Researchers Compete for Funding

By: PR Newswire | 12 Mar 2009 | 02:06 PM ET
SAN CLEMENTE, Calif., March 12, 2009 /PRNewswire via COMTEX/ — Adult Stem Cell scientists and businesses are concerned that President Obama’s executive order repealing restrictions on Embryonic Stem Cell research will have the unintended consequence of diverting attention and resources away from the promising Adult Stem Cell scientific advances.

STEMTech HealthSciences is a leading company in the field of Stem Cell Nutrition and its chief executive officer is speaking out to create awareness of Adult Stem Cell science’s need for continued support and resources. Adult Stem Cells are naturally created by a person’s own body while Embryonic Stem Cells are extracted from embryos.

“The amazing advances over the past few years in Adult Stem Cell science, including the Nobel Prize winning advances that led to the discovery that Adult Stem Cells travel to tissues and organs needing renewal and become cells of these organs and tissues, are at risk of being eclipsed because of the media and business furor over Embryonic Stem Cells” said STEMTech CEO Ray Carter.

According to Carter, Embryonic Stem Cell research is a multi-billion dollar industry with Wall Street, the media and now the U.S. government joining in to create visibility and mass funding. Meanwhile, the scientific progress made by companies such as STEMTech which owns the rights to the only patented product proven to enhance Adult Stem Cell release in a person’s own body goes relatively unnoticed.

While not a mediagenic billion dollar player however, STEMTech has grown into 8 countries since 2006 with its Stem Cell Nutrition product line which supports healthy Adult Stem Cell physiology.

Christian Drapeau, author of The Stem Cell Theory of Renewal (March 2009, Sutton Hart http://www.suttonhart.com) and pioneer of the Stem Cell Nutrition field, explains the StemEnhance(R) value proposition that “a natural, mild long term increase in the body’s level of circulating Adult Stem Cells delivers substantial wellness benefits”.

According to Christian Drapeau, who serves as STEMTech’s chief science officer, Adult Stem Cells have the greater potential for human wellness and he echoes Carter’s concern that President Obama’s removing restrictions Embryonic Stem Cell research could divert critical resources away from Adult Stem Cell research.

Media Contact: Maggie Jessup maggie@platformstrategy.com SOURCE STEMTech HealthSciences http://www.prnewswire.com Copyright (C) 2009 PR Newswire. All rights reserved -0-

Aphanizomenon flos-aquae (AFA) & Natural Killer (NK) Cell Release

Health Professionals Research Royal Victoria Hospital

stemcell-purple1-12Health Professionals Research

Study of Chlorophyll

Effect of dietary chlorophyll derivatives on mutagenesis and tumor cell growth

Chernomorsky S, Segelman A, Poretz RD. (1999). Teratog Carcinog Mutagen.19(5):313-22

Much attention in recent years has been given to the antigenotoxicity of chlorophyll. Chlorophyll, however, is known to be converted into pheophytin, pyropheophytin, and pheophorbide in processed vegetable food and following ingestion by humans. Studies were conducted on the antimutagenic and tumoricidal potencies of these compounds. All the chlorophyll derivatives tested exhibit identical antimutagenic effect towards 3-methylcholanthrene (3-MC), suggesting that the porphyrin nucleus may complex directly with the mutagen. It does not exclude, however, another mechanism of activity involving inactivation the enzymatic transformation of 3-MC. In contrast, the action of N’-nitro-N’-nitrosoguanidine (MNNG) depends upon structural differences between the chlorophyll derivatives. It is significantly lower when the phytol-containing pheophytin and pyropheophytin are tested as to that of the phytol-lacking pheophorbide. The higher concentrations of the chlorophyll derivatives were required to reduce the mutagenicity of MNNG than needed for 3-MC. The cytotoxicity of chlorophyll derivatives against tumor cells also was evaluated. The cellular uptake and inhibition of myeloma cell multiplicity were found to be greater for pheophorbide than for pheophytin. Calculated on the amount of cell associated chlorophyll derivative, however, pheophytin was more cytostatic/cytotoxic than pheophorbide. The results presented in this report indicate that food sources that yield chlorophyll derivatives may play a significant role in cancer prevention.

An Exciting New Discovery!

Recently the first stage of an extensive research project carried out at the Royal Victoria Hospital in Montreal, Canada produced some remarkable results. The project studies the effect of Aphanizomenon flos-aquae on the immune and endocrine systems, as well as on general blood physiology. It was discovered that eating AFA had a profound and unique effect on Natural Killer (NK) cells. The results were recently published under the title: Effects of the Blue Green Algae Aphanizomenon flos-aquae on Human Natural Killer Cells. It appears in Chapter 3.1 of the IBC Library Series, Volume 1911, Phytoceuticals: Examining the health benefit and pharmaceutical properties of natural antioxidants and phytochemicals.

NK cells have the ability to search for and recognize cells that are cancerous or have been infected by a virus, and kill them. The team of research scientists at the Royal Victoria Hospital, led by Dr. Gitte S. Jensen, discovered that eating Aphanizomenon flos-aquae triggers the movement of 40% of the circulating NK cells from the blood to the tissues where their main function is to perform immune surveillance and eliminate cancerous and virally-infected cells. Further research may prove that eating a small amount of AFA every day could assist in the prevention of cancer and viral infections. No other substance is known to trigger such a movement of NK cells in the body. This is very exciting news! We hope you will share it with everyone you know!_____________________________________________________

NOTE: These statements have not been evaluated by the U.S. Food &
Drug Administration. The information contained in this website, are not
intended to treat, cure or prevent any disease. Results may vary.

Patients First Act Adult Stem Cells HR 2807 & HR 877

Richard Burt M.D. has completed a study using adult stem cell therapy on patients that has been published in JAMA – The Journal of the American Medical Association. Three of his patients from the study that had received injections of their own adult stem cells, taken from their bone marrow, spoke in front of lawmakers in Washington DC. They are trying to get funding for the same adult stem cell therapy that has helped them. Dr. David Prentice PhD. of the Family Research Council thanked the bi-partisan group that sponsored the bill H.R. 2807 The Patient First Act that would seek funding for the therapies that wil help the patients first. The public should call lawmakers and have support them support the bill.

How can we approve Embryonic Stem Cell legislation? Especially when there is no proof of any true merit and comes with life threatening side effects… then hold out on funding for adult stem cell therapy which has scientific studies proving its effectiveness. The legislation that was introduced above H.R. 2807 was introduced but never made it out of committee.  See below.

H.R. 2807:  Patients First Act of 2007
  Introduced Jun 21, 2007
  Reported by Committee (did not occur)
  Voted on in House (did not occur)
  Voted on in Senate (did not occur)
  Signed by President (did not occur)
This bill never became law. This bill was proposed in a previous session of Congress. Sessions of Congress last two years, and at the end of each session all proposed bills and resolutions that haven’t passed are cleared from the books. Members often reintroduce bills that did not come up for debate under a new number in the next session.

So it was reintroduced on Feb. 4, 2009 as H.R. 877:  Patients First Act of 2009. It was submitted to the House Committee on Energy and Commerce which has 59 members. Here is a link to all the members and all the bills that they are overseeing http://twurl.nl/0mrnuo .

Please join with me and write your representatives and tell them we want H.R. 877  passed. We should have the opportunity to intensify stem cell research which has already been showing evidence of substantial clinical benefit to patients, and for other purposes, and in an ethical manner.  The latest info on the bill is below and I will continue to update it.

H.R. 877:  Patients First Act of 2009

  Introduced Feb 4, 2009
  Referred to Committee View Committee Assignments
  Reported by Committee (pending)
  Voted on in House (pending)
  Voted on in Senate (pending)
  Signed by President (pending)

This bill is in the first step in the legislative process. Introduced bills and resolutions first go to committees that deliberate, investigate, and revise them before they go to general debate. The majority of bills and resolutions never make it out of committee. [Last Updated: Mar 7, 2009 11:31AM]

For more information on stem cell enhancers which aid our bodies in releasing our own adult bone marrow stem cells feel free to visit my website www.stemcellhotline.com. Leave me a comment to let me know what you think of the politics involved with this subject.

CARDIOVASCULAR REVASCULARIZATION MEDICINE

CARDIOVASCULAR REVASCULARIZATION MEDICINE

SCIENTIFIC STUDIES – 
st-cardio-journalCARDIOVASCULAR REVASCULARIZATION MEDICINE
including Molecular Interventions
Posted January 1, 2008

Abstract – PubMed.gov

Description

Mobilization of human CD34+CD133+ and CD34+CD133%u2212 stem cells in vivo by consumption of an extract from Aphanizomenon flos-aquae-related to modulation of CXCR4 expression by an L-selectin ligand?

This article is not included in your organization’s subscription. However, you may be able to access this article under your organization’s agreement with Elsevier.
Gitte S. Jensen, Aaron N. Hartb, Lue A.M. Zaske, Christian Drapeau, Niraj Guptad, David J. Schaeffere and J. Alex Cruickshank

a. Holger NIS, 601 13 Avenue NE, Calgary, Alberta, Canada T2E 1C7

b. NIS Labs, 1437 Esplanade, Klamath Falls, OR, USA

c. StemTech Health Sciences Inc., 1011 Calle Amanecer, San Clemente, CA, USA

d. Cancer Treatment Center, Merle West Medical Center, 2610 Uhrmann Rd, Klamath Falls, OR, USA

e. Department of Veterinary Biosciences, College of Veterinary Medicine, University of Illinois at Urbana-Champaign, USA

The coauthor C. Drapeau is Chief Science Officer for StemTech Health Sciences, which distributes the product StemEnhance, used for the in vivo part of this paper. No other authors have any commercial interest in the subject matter. Available online 29 August 2007.

Abstract
Objective
The goal of this study was to evaluate effects on human stem cells in vitro and in vivo of an extract from the edible cyanobacterium Aphanizomenon flos-aquae (AFA) enriched for a novel ligand for human CD62L (L-selectin).

Experimental approach
Ligands for CD62L provide a mechanism for stem cell mobilization in conjunction with down-regulation of the CXCR4 chemokine receptor for stromal derived factor 1. Affinity immunoprecipitation was used to identify a novel ligand for CD62L from a water extract from AFA. The effects of AFA water extract on CD62L binding and CXCR4 expression was tested in vitro using human bone marrow CD34+ cells and the two progenitor cell lines, KG1a and K562. A double-blind randomized crossover study involving 12 healthy subjects evaluated the effects of consumption on stem cell mobilization in vivo.

Results
An AFA extract rich in the CD62L ligand reduced the fucoidan-mediated externalization of the CXCR4 chemokine receptor on bone marrow CD34+ cells by 30% and the CD62L+ CD34+ cell line KG1A by 50% but did not alter the CXCR4 expression levels on the CD34 cell line K562. A transient, 18% increase in numbers of circulating CD34+ stem cells maximized 1 hour after consumption (P<.0003). When 3 noncompliant volunteers were removed from analysis, the increase in CD34+ cells was 25% (P<.0001).

Conclusion
AFA water extract contains a novel ligand for CD62L. It modulates CXCR4 expression on CD34+ bone marrow cells in vitro and triggers the mobilization of CD34+ CD133+ and CD34+ CD133 cells in vivo.

Keywords: L-selectin; Ligand; Human; Adult stem cell; CD34; CD133; KG1a; K562; Bone marrow; Mobilization; Blue-green algae; Cyanobacteria; Aphanizomenon; In vivo; In vitro

Abbreviations: AFA, Aphanizomenon flos-aquae; PBMC, Peripheral blood mononuclear cells; PMN, Polymorph-nucleated cells

Article Outline
1. Introduction
2. Materials and methods
2.1. Buffers and media
2.2. Cyanobacterial extracts
2.3. Monoclonal antibodies
2.4. Capturing of ligand using Dynabeads and chimera proteins
2.5. Electrophoresis
2.6. Human subjects
2.7. Immunostaining for L-selectin
2.8. Immunostaining for CXCR4 expression on different types of progenitor cells
2.9. Induction of CXCR4 expression on various types of stem and progenitor-type cells
2.10. Study design for in vivo testing of consumption of an LSL-rich fraction of AFA
2.11. Statistical analysis
3. Results
3.1. AFA contains a ligand for human L-selectin (CD62L)
3.2. AFA-W specifically reduces TQ1 immunostaining of L-selectin on human PMN cells
3.3. AFA-W inhibits the fucoidan-induced CXCR4 expression on CD34+ cells from bone marrow and on the KG1a CD34bright cell line but not on the CD34%u2212 cell line K562
3.4. In vivo: consumption of an AFA extract rich in AFA-LSL resulted in a transient increase of circulating CD34+ cells
4. Discussion

Acknowledgements
References

Download Complete Article Here: http://twurl.nl/2ne65h

Can Adult Stem Cells Be The Answer to Optimal Health?

green-stem-cellI have been researching adult stem cell therapies, clinical trials, journals and scientific literature for the past 16 months. With the abundance of scientific studies and supporting documentation on its many confirmed successes, I find it difficult to still have to debate the use of embryonic stem cells as a viable option. With the amount of evidence piling up supporting adult stem cell therapy maybe soon we will be able to put the debate to rest.

Regenerative medicine using stem cells was listed as one of the Top Research Trends for 2009. Adult stem cells are the answer to our question of how to promote health.

Once the world begins to understand that we have scientific studies documenting the ability to increase the release by 3 to 4 million of our own adult stem cells from the bone marrow into the bloodstream, go to http://tinyurl.com/ajs6gl , using a natural supplement then we will truly begin to realize our future for optimal health starts today.

For more information: http://www.stemcellhotline.com/ or email askjacki@gmail.com

Story of Christian Drapeau MSc. and StemEnhance

christian-drapeau2This is the story of how Christian Drapeau MSc. Chief Science Officer & Co-Founder of StemTech Health Sciences helped develop StemEnhance
A little over two decades ago, a new herbal supplement named Aphanizomenon flos-aquae (AFA), an aquatic botanical, made its appearance on the marketplace. Rapidly, AFA became popular for the wide variety of health benefits reported by consumers. Over the years we identified the presence in AFA of various bioactive compounds such as phycocyanin, a strong natural anti-inflammatory compound, a polysaccharide supporting immune function, and phenylethylamine (PEA), a molecule knows as “the molecule of love,” which increases mental clarity and provides a sense of well-being. Nevertheless, in spite of the identification of these various components, many health benefits reported by consumers remained unexplained.
At the turn of the 21st century, data began appearing in the scientific literature describing the potential of embryonic stem cells (ESC). Embryonic stem cells were shown to have the ability to become any kind of cells in the body. Soon after, studies revealed that adult stem cells (ASC) also had the ability of becoming virtually any kind of cells in the body. When this discovery was made, we hypothesized that adult stem cells constituted the natural renewal system of the body, and we published this hypothesis in the journal, Medical Hypotheses (October 2002). Our idea at the time was this: if adult stem cells indeed constituted the natural renewal system of the body, with adult stem cells being able to become any cell type of the body, then supporting this process could lead to a wide variety of health benefits. Given the broad spectrum of benefits reported by AFA consumers, we simply hypothesized that AFA was supporting aspects of stem cell physiology.
With this in mind, we initiated a series of laboratory experiments and soon discovered that consumption of large quantity of AFA (greater than 5 grams) increased the number of circulating stem cells by up to 30%. As we pursued our investigation to identify the compound in AFA responsible for this effect, we actually identified two specific compounds supporting both the release of stem cells from the bone marrow and their migration out of the blood into tissues. We then proceeded to concentrate these compounds out of AFA, achieving 5:1 concentrates for both compounds, and blended these compounds to make StemEnhance. One gram of StemEnhance supports the release of stem cells from the bone marrow and increases the number of stem cells from the bone marrow and increases the number of circulating stem cells by up to 30%. StemEnhance also concentrates phycocyanin and PEA, other important compounds found in AFA.
StemEnhance is a natural product made of 100% organic AFA and manufactured in accordance with GMP regulations. The powder is encapsulated and bottled in a pharmaceutical grade facility, providing the highest quality possible. Each lot of StemEnhance is tested for any potential contaminants, according to a stringent quality control program.
When asked why would one want to take StemEnhance, the answer is simply to support the body’s natural process of maintaining optimal health. Supporting stem cell physiology everyday by increasing the number of circulating stem cells is one of the wisest decisions one can make to regain and maintain optimal health.
Jacki Smith  – Health Coach 817.510.3600
askjacki@gmail.com   www.stemcellhotline.com